Primary Identifier | MGI:2443135 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 241134 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in neuron projection morphogenesis and phosphatidylinositol 3-kinase/protein kinase B signal transduction. Is expressed in cortical plate. Orthologous to human NYAP2 (neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2). PHENOTYPE: Triple KO of Nyap1, Nyap2 and Myo16 results in decreased brain weight and cortex and striatum size and reduced neurite length in cortical neurons. [provided by MGI curators] |