| Primary Identifier | MGI:1309481 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 14897 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable nuclear thyroid hormone receptor binding activity and ubiquitin protein ligase activity. Involved in regulation of embryonic development. Predicted to be located in nucleoplasm. Predicted to be active in nuclear speck. Is expressed in several structures, including brain and genitourinary system. Human ortholog(s) of this gene implicated in Clark-Baraitser syndrome. Orthologous to human TRIP12 (thyroid hormone receptor interactor 12). PHENOTYPE: Mice homozygous for a targeted allele exhibit complete embryonic lethality during organogenesis associated with embryonic growth retardation and abnormal placenta development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
