Primary Identifier | MGI:3702467 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 434484 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in nucleus. Orthologous to human SP140 (SP140 nuclear body protein) and SP140L (SP140 nuclear body protein like). PHENOTYPE: Mice homozygous for a null allele exhibit increased susceptibility to M. tuberculosis infection. [provided by MGI curators] |