Primary Identifier | MGI:1927594 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 64294 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP binding activity. Involved in positive regulation of extrinsic apoptotic signaling pathway. Located in lysosome. Is expressed in several structures, including central nervous system; genitourinary system; and retina. Orthologous to human ITM2C (integral membrane protein 2C). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no alterations in the development, maturation and differentiation of B-lymphocytes or production of antibodies by antibody secreting cells. [provided by MGI curators] |