Primary Identifier | MGI:2685064 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 227326 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cannabinoid receptor activity. Predicted to be involved in several processes, including bone resorption; negative regulation of osteoclast differentiation; and positive regulation of intracellular signal transduction. Predicted to be active in plasma membrane. Is expressed in cerebral cortex; forebrain; neural retina; and retina. Orthologous to human GPR55 (G protein-coupled receptor 55). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased bone volume due to impaired osteoclast function in male mice. Female mice exhibit a milder phenotype. [provided by MGI curators] |