| Primary Identifier | MGI:97286 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 17975 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables PH domain binding activity; RNA binding activity; and insulin receptor substrate binding activity. Acts upstream of or within several processes, including cellular response to epidermal growth factor stimulus; cellular response to leukemia inhibitory factor; and negative regulation of insulin receptor signaling pathway. Located in nucleolus and nucleoplasm. Is active in cornified envelope. Is expressed in several structures, including 1st branchial arch mandibular component; blastocyst; central nervous system; early embryo; and tooth. Orthologous to human NCL (nucleolin). PHENOTYPE: Mice homozygous for a null allele exhibit complete preweaning lethality while cultured neurons from heterozygotes exhibit accelerated axonal outgrowth. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
