| Primary Identifier | MGI:97803 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 19231 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone binding activity and histone chaperone activity. Involved in chromatin organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; extraembryonic component; and genitourinary system. Used to study polycystic kidney disease and pulmonary emphysema. Orthologous to human PTMA (prothymosin alpha). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality while heterozygotes show decreased body weight and body temperature, hypoactivity, increased anxiety-like behaviors, impaired learning and memory, and defects in adult hippocampal neurogenesis and long term potentiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
