Primary Identifier | MGI:1344417 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 23956 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables exo-alpha-sialidase activity. Involved in ganglioside catabolic process and oligosaccharide catabolic process. Predicted to be located in cytosol. Predicted to be part of catalytic complex. Predicted to be active in lysosome and membrane. Is expressed in brain. Orthologous to human NEU2 (neuraminidase 2). PHENOTYPE: Homozygous null mice show increased triglyceride and free fatty acids with age, development of fatty liver, impaired muscle differentiation and altered muscle morphology, poor exercise performance and obesity with age. [provided by MGI curators] |