| Primary Identifier | MGI:2181435 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 171382 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium channel activity and identical protein binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including intracellular calcium ion homeostasis; response to cold; and thermoception. Located in external side of plasma membrane and membrane raft. Is expressed in dorsal root ganglion; inferior vagus ganglion; lumbar dorsal root ganglion; and vagus ganglion. Orthologous to human TRPM8 (transient receptor potential cation channel subfamily M member 8). PHENOTYPE: Mice homozygous for a null allele exhibit decreased sensitivity to cold and reduced response to cold stimuli. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
