| Primary Identifier | MGI:1858418 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 51801 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables coreceptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in extracellular space. Predicted to be part of CGRP receptor complex. Predicted to be active in cell surface. Predicted to colocalize with plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; bone; brain; and reproductive system. Orthologous to human RAMP1 (receptor activity modifying protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit high systolic blood pressure due to a disruption in vasodilatory regulation as well as significantly increased serum levels of proinflammatory cytokines following LPS administration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
