Primary Identifier | MGI:1929735 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 65247 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within male genitalia development. Predicted to be part of ubiquitin ligase complex. Orthologous to human ASB1 (ankyrin repeat and SOCS box containing 1). PHENOTYPE: Homozygous mutation of this gene results in spleen hypocellularity, decreased spermatogenesis, and thickening of the skin in male animals. [provided by MGI curators] |