Primary Identifier | MGI:1194891 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 14733 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fibroblast growth factor binding activity and laminin binding activity. Involved in negative regulation of fibroblast growth factor receptor signaling pathway and positive regulation of skeletal muscle cell differentiation. Located in extracellular matrix and membrane raft. Is active in synapse. Is expressed in several structures, including alimentary system; limb; metanephros; musculoskeletal system; and nervous system. Orthologous to human GPC1 (glypican 1). PHENOTYPE: Homozygous mutant mice exhibit a reduced brain size with mild cerebellar patterning defects, but are otherwise viable and fertile. [provided by MGI curators] |