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Protein Coding Gene : Dtymk deoxythymidylate kinase
Primary Identifier  MGI:108396 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  21915
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables thymidylate kinase activity. Acts upstream of or within cellular response to growth factor stimulus and dTDP biosynthetic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion and nucleus. Is expressed in several structures, including alimentary system; forebrain; genitourinary system; midbrain; and respiratory system. Orthologous to human DTYMK (deoxythymidylate kinase).
PHENOTYPE: Homozygous mice for a null allele exhibit embryonic lethality before E12.5. [provided by MGI curators]
  • synonyms:
  • DNA segment, Chr 10, ERATO Doi 203, expressed,
  • mtmk,
  • deoxythymidylate kinase,
  • Tmk,
  • MGI:1261792,
  • MGD-MRK-37438,
  • AU044245,
  • thymidylate kinase,
  • CDC8,
  • D10Ertd203e,
  • Dtymk,
  • expressed sequence AU044245,
  • MGI:2138504,
  • TYPK
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2 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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