Primary Identifier | MGI:106018 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 20452 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. Involved in sialylation. Predicted to be located in Golgi apparatus. Is expressed in several structures, including central nervous system; gut; hemolymphoid system gland; lung; and sensory organ. Orthologous to human ST8SIA4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4). PHENOTYPE: Homozygous null adult mice exhibit impaired long term potentiation and impaired long term depression in hippocampal CA1 synapses. [provided by MGI curators] |