Primary Identifier | MGI:2138327 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 98432 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine phosphatase activity. Involved in regulation of T cell anergy. Acts upstream of or within entrainment of circadian clock. Predicted to be located in nuclear membrane; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in ventricular layer. Orthologous to human PHLPP1 (PH domain and leucine rich repeat protein phosphatase 1). PHENOTYPE: Mice homozygous for a null mutation display impairment in the ability to stabilize the circadian period after light induced resetting. [provided by MGI curators] |