Primary Identifier | MGI:3573933 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 20248 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in several cellular components, including cytoplasmic vesicle; cytosol; and extracellular exosome. Predicted to be active in extracellular space. Orthologous to human SERPINB3 (serpin family B member 3) and SERPINB4 (serpin family B member 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced susceptibility to allergen-induced airway hyperresponsiveness. [provided by MGI curators] |