Primary Identifier | MGI:97609 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 18788 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Is active in cornified envelope. Is expressed in several structures, including genitourinary system; immune system; mesothelium; respiratory system; and skin. Orthologous to human SERPINB2 (serpin family B member 2). PHENOTYPE: Homozygous inactivation of this gene leads to a slight to mild reduction in platelet, lymphocyte, neutrophil, and monocyte cell number. [provided by MGI curators] |