| Primary Identifier | MGI:96571 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 16324 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity and protein homodimerization activity. Involved in several processes, including cellular response to insulin stimulus; cellular response to leptin stimulus; and positive regulation of ovulation. Acts upstream of or within negative regulation of insulin secretion; oocyte development; and positive regulation of apoptotic signaling pathway. Located in cell periphery and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; early conceptus; eye; and genitourinary system. Orthologous to human INHBB (inhibin subunit beta B). PHENOTYPE: Some homozygotes for targeted null mutations exhibit open eyes at birth and impaired maternal nuturing. Mutant females for one line exhibit extended gestation length, retarded mammary duct elongation and alveolar morphogenesis, and are unable to nurse their pups. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
