Primary Identifier | MGI:1099792 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 19258 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glutamate receptor binding activity and non-membrane spanning protein tyrosine phosphatase activity. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; immune system; and respiratory system. Orthologous to human PTPN4 (protein tyrosine phosphatase non-receptor type 4). PHENOTYPE: Mice homozygous for a null allele exhibit impaired coordination, abnormal eye blink conditioning behavior, and reduced long term depression. [provided by MGI curators] |