| Primary Identifier | MGI:2441720 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 319229 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables secretin receptor activity. Involved in several processes, including diet induced thermogenesis; intracellular water homeostasis; and renal water absorption. Predicted to be located in cytoplasmic microtubule. Predicted to be active in plasma membrane. Orthologous to human SCTR (secretin receptor). PHENOTYPE: Homozygotes for a null allele show polydipsia, polyuria, decreased urine osmolality, higher serum glucose levels, kidney glomerular and tubular pathology, and impaired renal water reabsorption. Homozygotes for a different null allele show impaired synaptic plasticity and social behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
