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Protein Coding Gene : Mgat5 mannoside acetylglucosaminyltransferase 5
Primary Identifier  MGI:894701 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  107895
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity. Acts upstream of or within protein N-linked glycosylation. Located in Golgi apparatus. Is expressed in several structures, including alimentary system; brain; integumental system; sensory organ; and urinary system. Orthologous to human MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase).
PHENOTYPE: Mice homozygous for deficiencies in this gene have immune system abnormalities and reduced cancer growth and metastasis. [provided by MGI curators]
  • synonyms:
  • MGI:2444778,
  • RIKEN cDNA 4930471A21 gene,
  • MGI:1923060,
  • beta1,6N-acetylglucosaminyltransferase V,
  • MGI:2138276,
  • expressed sequence AI480971,
  • RIKEN cDNA 5330407H02 gene,
  • AI480971,
  • 4930471A21Rik,
  • Mgat5,
  • 5330407H02Rik,
  • mannoside acetylglucosaminyltransferase 5,
  • GlcNAc-TV
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3 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

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Disease

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