| Primary Identifier | MGI:1919410 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 72160 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable zinc ion binding activity. Predicted to be involved in myelination; zinc export across plasma membrane; and zinc ion import into synaptic vesicle. Located in synaptic vesicle membrane. Is active in intracellular vesicle and plasma membrane. Is expressed in cerebral cortex; cortical layer V; cortical subplate; heart; and limb. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 25. Orthologous to human TMEM163 (transmembrane protein 163). PHENOTYPE: Mice homozygous for a null allele exhibit absent platelet dense granules, impaired platelet mepacrine uptake, ATP release, and zinc homeostasis, decreased platelet aggregation, and increased bleeding time. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
