Primary Identifier | MGI:104965 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 22789 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in binding activity of sperm to zona pellucida. Acts upstream of or within single fertilization. Located in acrosomal vesicle; cell body; and plasma membrane. Part of zona pellucida receptor complex. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human C4BPA (complement component 4 binding protein alpha). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal fertility and sperm morphology and physiology. [provided by MGI curators] |