| Primary Identifier | MGI:1890472 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 329244 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity. Involved in negative regulation of low-density lipoprotein particle clearance. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway; positive regulation of intrinsic apoptotic signaling pathway; and reactive oxygen species metabolic process. Predicted to be located in extracellular space. Orthologous to human IL19 (interleukin 19). PHENOTYPE: Mice homozygous for a knock-out allele exhibit interleukin-23 (IL-23)-dependent epidermal hyperplasia. Mice homozygous for a different knock-out allele exhibit increased susceptibility to induced colitis with reduced B cell infiltration in chronic colitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
