Primary Identifier | MGI:1919669 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 108900 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to act upstream of or within positive regulation of apoptotic process. Predicted to be located in intracellular membrane-bounded organelle and membrane. Predicted to be active in cytosol. Is expressed in brain; esophagus; genitourinary system; and trachea. Orthologous to several human genes including FAM72A (family with sequence similarity 72 member A). PHENOTYPE: Mice homozygous for a null allele exhibit impaired class switch recombination and somatic hypermutation with increased germinal center B cell numbers. [provided by MGI curators] |