Primary Identifier | MGI:1925064 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 213452 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in several processes, including cellular response to fibroblast growth factor stimulus; positive regulation of kinase activity; and positive regulation of signal transduction. Located in apical plasma membrane; basolateral plasma membrane; and cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and skin. Human ortholog(s) of this gene implicated in CAKUT1 and hereditary spastic paraplegia 23. Orthologous to human DSTYK (dual serine/threonine and tyrosine protein kinase). PHENOTYPE: Homozygous knockout results in impaired spatial learning. [provided by MGI curators] |