Primary Identifier | MGI:2444211 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 108954 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein phosphatase regulator activity. Acts upstream of or within ER overload response and response to hydrogen peroxide. Part of protein phosphatase type 1 complex. Is expressed in compacted morula and inner cell mass. Orthologous to human PPP1R15B (protein phosphatase 1 regulatory subunit 15B). PHENOTYPE: Mice homozygous for a null allele die within the first day after birth with decreased weight at birth and red blood cell counts. [provided by MGI curators] |