Primary Identifier | MGI:108384 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 12227 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription corepressor activity. Acts upstream of or within several processes, including central nervous system development; negative regulation of neuroblast proliferation; and skeletal muscle cell differentiation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human BTG2 (BTG anti-proliferation factor 2). PHENOTYPE: Homozygous null Btg2tm1Wbh mice do not exhibit an overt phenotype. Homozygous null Btg2tm1Spo mice exhibit posterior homeotic transformations of the axial vertebrae. [provided by MGI curators] |