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Protein Coding Gene : Ppp1r12b protein phosphatase 1, regulatory subunit 12B
Primary Identifier  MGI:1916417 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  329251
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable enzyme inhibitor activity and myosin phosphatase regulator activity. Predicted to be involved in neuron projection morphogenesis. Located in A band and Z disc. Orthologous to human PPP1R12B (protein phosphatase 1 regulatory subunit 12B).
PHENOTYPE: Mice with loss of expression in adult cardiomyocytes display blunted cardiac hypertrophic response to pressure overload. Mice homozygous for a null allele on a C57BL/6N background display improved cardiac function. [provided by MGI curators]
  • synonyms:
  • AI132431,
  • 1810037O03Rik,
  • RIKEN cDNA 1810037O03 gene,
  • protein phosphatase 1, regulatory subunit 12B,
  • Ppp1r12b,
  • RIKEN cDNA 9530009M10 gene,
  • expressed sequence AI132431,
  • MGI:2444883,
  • MGI:2138164,
  • 9530009M10Rik
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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