| Primary Identifier | MGI:108027 | Organism | mouse, laboratory |
| Chromosome | 1 | Mgi Type | polymorphic pseudogene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein tyrosine phosphatase activity. Acts upstream of or within several processes, including DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; negative regulation of insulin secretion; and type B pancreatic cell proliferation. Predicted to be located in membrane. Is expressed in several structures, including early conceptus; embryo mesenchyme; gonad; limb ectoderm; and skeleton. Orthologous to human PTPRVP (protein tyrosine phosphatase receptor type V, pseudogene). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased resistance to diet-induced obesity, decreased circulating glucose levels, and decreased suseptibility to death induced by streptozotocin treatment. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
