Primary Identifier | MGI:1928503 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 171469 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled peptide receptor activity; peptide binding activity; and prosaposin receptor activity. Involved in cellular response to reactive oxygen species; negative regulation of systemic arterial blood pressure; and positive regulation of MAPK cascade. Acts upstream of or within negative regulation of cell differentiation; negative regulation of smoothened signaling pathway; and positive regulation of cerebellar granule cell precursor proliferation. Located in plasma membrane. Is expressed in brain; dentate gyrus subgranular zone; spinal cord; spinal cord gray matter; and spinal cord white matter. Orthologous to human GPR37L1 (G protein-coupled receptor 37 like 1). PHENOTYPE: Mice homozygous for a knock-out allele may exhibit no abnormal phenotype, precocious cerebellum development and improved motor functions or abnormal blood pressure in female mice. [provided by MGI curators] |