| Primary Identifier | MGI:1915247 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 67997 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be involved in chromatin looping and chromatin remodeling. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including early conceptus; eye; face; lip; and oocyte. Human ortholog(s) of this gene implicated in orofaciodigital syndrome V. Orthologous to human DDX59 (DEAD-box helicase 59). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete embryonic lethality by E9.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
