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Protein Coding Gene : Lhx9 LIM homeobox protein 9

Primary Identifier  MGI:1316721 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  16876
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within cell population proliferation and gonad development. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; heart and pericardium; limb; nervous system; and sensory organ. Orthologous to human LHX9 (LIM homeobox 9).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit failed proliferation of the somatic cells of the genital ridge resulting in lack of discrete gonad formation, infertility in both sexes, and female-like genitalia in genetically male mice. [provided by MGI curators]
  • synonyms:
  • MGI:2138632,
  • RIKEN cDNA 3110009O07 gene,
  • LH2B,
  • Lhx9 alpha,
  • BB104635,
  • LIM homeobox protein 9,
  • MGI:1920327,
  • 3110009O07Rik,
  • Lhx9,
  • expressed sequence BB104635

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For