Primary Identifier | MGI:2180585 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 246709 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within G protein-coupled receptor signaling pathway and negative regulation of G protein-coupled receptor signaling pathway. Located in cytosol; nucleus; and plasma membrane. Is expressed in several structures, including gut and hemolymphoid system. Orthologous to human RGS13 (regulator of G protein signaling 13). PHENOTYPE: Mice homozygous for a null allele exhibit increased mast cell degranulation and increased anaphylaxis. [provided by MGI curators] |