Primary Identifier | MGI:1354694 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 50778 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G-protein alpha-subunit binding activity and GTPase activator activity. Acts upstream of or within response to bacterium. Predicted to be located in cytoplasmic side of plasma membrane and cytosol. Orthologous to human RGS1 (regulator of G protein signaling 1). PHENOTYPE: Homozygous null mice display increased splenic B cell germinal centers, increased chemotactic responses in B cells and immature dendritic cells, and decreased antibody secreting cell numbers. [provided by MGI curators] |