Primary Identifier | MGI:98090 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 20028 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in regulation of G protein-coupled receptor signaling pathway and visual perception. Located in photoreceptor outer segment. Is expressed in several structures, including central nervous system; foot; skeleton; and spinal nerve plexus. Orthologous to human PDC (phosducin). PHENOTYPE: Homozygous null mice display normal retinal morphology and rod function with reduced transducin (Gnat1) translocation. Mice homozygous for a different knock-out allele exhibit large pupils, increased blood pressure, age-related vascular smooth muscle hypertrophy, and stress-induced hypertension. [provided by MGI curators] |