Primary Identifier | MGI:108177 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 13211 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables regulatory region RNA binding activity. Involved in positive regulation of interleukin-18 production; pyroptotic inflammatory response; and regulation of defense response. Acts upstream of or within cellular response to heat and circadian rhythm. Located in nucleolus. Is expressed in several structures, including alimentary system; central nervous system; lung; salivary gland primordium; and sensory organ. Orthologous to human DHX9 (DExH-box helicase 9). PHENOTYPE: Homozygotes die in embryonic stages with massive apoptotic cell death in embryonic ectodermal cells. [provided by MGI curators] |