Primary Identifier | MGI:1098567 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 11899 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within locomotory behavior; neuron cell-cell adhesion; and neuron migration. Located in endosome and external side of plasma membrane. Is expressed in several structures, including central nervous system; future brain; and retina. Orthologous to human ASTN1 (astrotactin 1). PHENOTYPE: Homozygous mutation of this gene results in reduced cerebellum size, abnormal Purkinje cell morphology, and reduced coordination performance on the Rotarod test. [provided by MGI curators] |