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Protein Coding Gene : Pappa2 pappalysin 2
Primary Identifier  MGI:3051647 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  23850
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable metalloendopeptidase activity. Acts upstream of or within bone morphogenesis. Predicted to be located in apical plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; long bone; nervous system; and retina layer. Orthologous to human PAPPA2 (pappalysin 2).
PHENOTYPE: Mice homozygous for a null mutation are viable and fertile but display postnatal growth retardation that is more pronounced in females compared to males. [provided by MGI curators]
  • synonyms:
  • PLAC3,
  • Pappe,
  • placenta-specific 3,
  • PAPP-A2,
  • pappalysin 2,
  • Pappa2,
  • pregnancy-associated plasma protein-E,
  • pregnancy-associated plasma preproprotein-A2
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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