| Primary Identifier | MGI:2665790 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 329278 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and integrin binding activity. Involved in several processes, including generation of neurons; negative regulation of canonical Wnt signaling pathway; and negative regulation of osteoblast differentiation. Acts upstream of or within axonogenesis and cell-matrix adhesion. Located in several cellular components, including CA3 pyramidal cell dendrite; hippocampal mossy fiber expansion; and neuronal cell body. Part of tenascin complex. Is expressed in several structures, including cranium; dura mater; forelimb; palatal shelf; and periosteum. Orthologous to human TNN (tenascin N). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced food intake, body weight and lifespan, and major defects in the alveolar bone and periodontal ligament of growing incisors while molars remain unaffected. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
