| Primary Identifier | MGI:1270839 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 12301 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables molecular adaptor activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in cytoplasm and nuclear envelope lumen. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including alimentary system; genitourinary system; liver lobe; nervous system; and sensory organ. Orthologous to human CACYBP (calcyclin binding protein). PHENOTYPE: Mice homozygous for a null allele exhibit reduced thymus and spleen cellularity, and defects in TCR-rearrangement. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
