| Primary Identifier | MGI:2685397 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 381305 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity and zinc ion binding activity. Involved in several processes, including P-body assembly; negative regulation of lymphocyte activation; and regulation of RNA metabolic process. Acts upstream of or within several processes, including T cell activation; hematopoietic or lymphoid organ development; and lymphocyte homeostasis. Located in P-body and cytoplasmic stress granule. Used to study peripheral T-cell lymphoma and systemic lupus erythematosus. Orthologous to human RC3H1 (ring finger and CCCH-type domains 1). PHENOTYPE: A single recessive mutation on this gene resulted in severe autoimmune disease with phenotype resembling human systemic lupus erythematosus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
