Primary Identifier | MGI:894320 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 11758 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 1-acylglycerophosphocholine O-acyltransferase activity; peroxidase activity; and phospholipase A2 activity. Acts upstream of or within bleb assembly and response to reactive oxygen species. Located in cytosol. Is expressed in several structures, including alimentary system; central nervous system; liver and biliary system; respiratory system; and sensory organ. Orthologous to human PRDX6 (peroxiredoxin 6). PHENOTYPE: Mice homozygous for disruptions of this gene show no macroscopic or microscopic abnormalities. However, they have an increased susceptibility to oxidative stress. [provided by MGI curators] |