| Primary Identifier | MGI:1202864 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 17926 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables receptor tyrosine kinase binding activity. Involved in several processes, including ERBB2-ERBB3 signaling pathway; neurogenesis; and skeletal muscle hypertrophy. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and node of Ranvier. Is expressed in several structures, including brain; eye; genitourinary system; lung; and meninges. Used to study open-angle glaucoma. Human ortholog(s) of this gene implicated in juvenile glaucoma; low tension glaucoma; ocular hypertension; open-angle glaucoma; and primary open angle glaucoma. Orthologous to human MYOC (myocilin). PHENOTYPE: Homozygous null mice are viable and fertile and display no ocular abnormalities at the light and ultrastructural microscopic levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
