Primary Identifier | MGI:1310002 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 14261 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables hypotaurine monooxygenase activity. Involved in taurine biosynthetic process. Acts upstream of or within energy homeostasis; negative regulation of fatty acid oxidation; and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in brain; cortical renal tubule; late tubule; and testis. Orthologous to human FMO1 (flavin containing dimethylaniline monoxygenase 1). PHENOTYPE: Mice homozygous for a null mutation display decreased dopaminerginc neuron numbers and increased cytokine levels in the substania nigra. [provided by MGI curators] |