Primary Identifier | MGI:1100496 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 14262 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable NADP binding activity; amino acid binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Predicted to be involved in taurine biosynthetic process and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in hypertension; inherited metabolic disorder; and trimethylaminuria. Orthologous to human FMO3 (flavin containing dimethylaniline monoxygenase 3). PHENOTYPE: Mice homozygous for a null allele exhibit reduced total body fat. [provided by MGI curators] |