| Primary Identifier | MGI:2449121 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 171567 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 3'-5' exonuclease activity and protein kinase activity. Involved in flagellated sperm motility. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; epithelial cilium movement involved in extracellular fluid movement; and intraciliary transport. Located in axonemal microtubule; centrosome; and ciliary basal body. Is active in axonemal A tubule inner sheath and sperm flagellum. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study hydrocephalus. Orthologous to human NME7 (NME/NM23 family member 7). PHENOTYPE: Homozygous mice exhibit hydrocephaly, domed skulls and 50% exhibit situs inversus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
