Primary Identifier | MGI:104593 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 16963 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chemokine activity. Involved in several processes, including mature natural killer cell chemotaxis; positive regulation of leukocyte migration; and positive regulation of production of molecular mediator of immune response. Acts upstream of or within chemotaxis and establishment of localization in cell. Located in extracellular space. Orthologous to human XCL1 (X-C motif chemokine ligand 1) and XCL2 (X-C motif chemokine ligand 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased stimulated cytotoxic T cell cytolysis. [provided by MGI curators] |