Primary Identifier | MGI:2660854 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 271639 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATPase binding activity; bicarbonate binding activity; and manganese ion binding activity. Predicted to be involved in several processes, including plasma membrane bounded cell projection organization; positive regulation of apoptotic process; and positive regulation of metabolic process. Located in apical plasma membrane. Is expressed in several structures, including gonad; heart; hemolymphoid system gland; liver; and lung. Orthologous to human ADCY10 (adenylate cyclase 10). PHENOTYPE: Homozygous null male mutants are infertile with a severe sperm motility defect, female null mutants are fertile. Females exhibit increased cholesterol and triglyceride levels while both sexes have a slight increase in heart rate. [provided by MGI curators] |