Primary Identifier | MGI:1098434 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 19737 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of vascular associated smooth muscle cell proliferation. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and visual system. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma and essential hypertension. Orthologous to human RGS5 (regulator of G protein signaling 5). PHENOTYPE: Mice homozygous for a targeted mutation appear normal. [provided by MGI curators] |